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Novel functional assay for proteases and modulators

AbstractProteases play a critical role in many cellular functions and have been an attractive therapeutic target due to their involvement in a number of disease processes. One prominent example is the...

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Intratumoural heterogeneity generated by Notch signalling promotes small-cell...

In a mouse model of small-cell lung cancer and in human tumours, activation of the Notch pathway can lead to a cell fate switch of neuroendocrine cells to less proliferative non-neuroendocrine cells,...

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Programming by Demonstration in Augmented Reality for the Motion Planning of...

AbstractThis study presents a programming by demonstration (PbD) interface in augmented reality for motion planning in a three-axis CNC glue dispenser. The interface assists a human planner to...

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